Q-omics provides the consensus-scored ALDH7A1P1 profile across patient tissues and cancer cell-line models. ALDH7A1P1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, ALDH7A1P1 is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, ALDH7A1P1 RNA expression shows 14,282 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, COAD, and THYM as cancer lineages where ALDH7A1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
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This table summarizes ALDH7A1P1 survival associations across molecular data types. ALDH7A1P1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ALDH7A1P1 RNA expression–survival associations across cancer types. High ALDH7A1P1 expression shows unfavorable associations in KICH, LUAD, LGG and BLCA, but favorable associations in KIRC and UCS. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for ALDH7A1P1 RNA expression.
This table summarizes ALDH7A1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for ALDH7A1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ALDH7A1P1 shows lower tumor expression in KICH, KIRP, THCA and BLCA and higher tumor expression in COAD and READ. The COAD box plot shows higher ALDH7A1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.796, t-test p < 0.001).
This table shows molecular features associated with ALDH7A1P1 in patient tissues and cancer cell lines. In patient samples, ALDH7A1P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.