ALDH7A1

Across TCGA cell cohorts, ALDH7A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,519 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALDH7A1-associated GO terms across cancer lineages are L-lysine catabolic process, Choline catabolic process, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with ALDH7A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ALDH7A1-to-partner and partner-to-ALDH7A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-lysine catabolic process grouped by ALDH7A1-low versus ALDH7A1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH7A1→partner) and Y-score (partner→ALDH7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	L-lysine catabolic process →	+0.162	+1.177	<.001	<.001	3	7
LUNG_SCLC	Choline catabolic process →	+0.633	+3.249	.007	.001	3	7
URINARY_TRACT	Proton motive force-driven mitochondrial ATP synthesis →	+0.063	+2.441	<.001	.005	3	7
LUNG_SCLC	Choline metabolic process →	+0.620	+3.048	.002	<.001	3	6
LUNG_SCLC	Regulation of endosome to plasma membrane protein transport →	+0.202	+4.469	<.001	<.001	3	6
BLOOD_Lymphoma	Negative regulation of calcium ion export across plasma membrane →	+0.064	+1.001	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,519 associations by consensus.

L-lysine catabolic process by ALDH7A1 expression — PANCREAS

Explore this box plot interactively →