ALDH6A1

Across TCGA patient cohorts, ALDH6A1 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,450 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALDH6A1-associated proteins across cancer lineages are BCKDHB, TUFM, and CBR4. Each is linked with ALDH6A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ALDH6A1-to-partner and partner-to-ALDH6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH6A1 versus BCKDHB in OV, with a Pearson correlation of 0.58.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH6A1→partner) and Y-score (partner→ALDH6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BCKDHB →	+0.890	+1.032	<.001	<.001	3	10
OV	TUFM →	+0.636	+1.145	<.001	.001	3	10
OV	CBR4 →	+0.732	+0.976	<.001	<.001	3	10
BRCA	MCCC2 →	+0.673	+0.580	<.001	<.001	3	10
PDAC	SUCLG1 →	+0.438	+0.453	<.001	<.001	3	9
GBM	SUCLG2 →	+0.484	+0.513	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,450 associations by consensus.

ALDH6A1 vs BCKDHB — OV

Explore this scatter interactively →