ALDH6A1

Across TCGA cell cohorts, ALDH6A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,066 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ALDH6A1-associated GO terms across cancer lineages are Thymine metabolic process, Pyrimidine nucleobase catabolic process, and Thymine catabolic process. Each is linked with ALDH6A1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ALDH6A1-to-partner and partner-to-ALDH6A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Thymine metabolic process grouped by ALDH6A1-low versus ALDH6A1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH6A1→partner) and Y-score (partner→ALDH6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Thymine metabolic process →	+1.287	+1.179	<.001	<.001	3	14
LARGE_INTESTINE	Pyrimidine nucleobase catabolic process →	+1.287	+1.179	<.001	<.001	3	14
LARGE_INTESTINE	Thymine catabolic process →	+1.287	+1.179	<.001	<.001	3	14
BREAST	Branched-chain amino acid catabolic process →	+0.098	+0.781	<.001	<.001	3	13
BREAST	Branched-chain amino acid metabolic process →	+0.099	+0.828	<.001	<.001	3	13
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.129	+0.620	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,066 associations by consensus.

Thymine metabolic process by ALDH6A1 expression — LARGE_INTESTINE

Explore this box plot interactively →