ALDH5A1

Across TCGA patient cohorts, ALDH5A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,639 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALDH5A1-associated proteins across cancer lineages are PLAU, DDAH1, and ERO1A. Each is linked with ALDH5A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALDH5A1-to-partner and partner-to-ALDH5A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH5A1 versus PLAU in GBM, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH5A1→partner) and Y-score (partner→ALDH5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLAU →	-0.746	-0.588	<.001	<.001	3	6
CCRCC	DDAH1 →	+0.505	+0.506	<.001	<.001	3	5
GBM	ERO1A →	-0.540	-0.614	<.001	<.001	3	5
LSCC	LGALS1_S30 →	-0.715	-0.687	<.001	<.001	3	5
LSCC	LOXL2 →	-0.807	-0.574	<.001	.008	3	5
GBM	PLAUR →	-0.578	-0.615	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,639 associations by consensus.

ALDH5A1 vs PLAU — GBM

Explore this scatter interactively →