ALDH5A1

Across TCGA patient cohorts, ALDH5A1 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,681 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALDH5A1-associated proteins across cancer lineages are AIFM1, BCKDHB, and TUFM. Each is linked with ALDH5A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ALDH5A1-to-partner and partner-to-ALDH5A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH5A1 versus AIFM1 in OV, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH5A1→partner) and Y-score (partner→ALDH5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AIFM1 →	+0.675	+0.689	<.001	<.001	3	10
HNSC	BCKDHB →	+0.532	+0.661	<.001	<.001	3	10
COAD	TUFM →	+0.350	+0.562	<.001	<.001	3	10
CCRCC	BDH1 →	+0.851	+0.477	<.001	<.001	3	10
LUAD	COQ7 →	+0.487	+0.627	<.001	<.001	3	10
LUAD	CPT2 →	+0.516	+0.702	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,681 associations by consensus.

ALDH5A1 vs AIFM1 — OV

Explore this scatter interactively →