ALDH5A1

Across TCGA cell cohorts, ALDH5A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,116 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALDH5A1-associated GO terms across cancer lineages are Response to triglyceride, C-terminal protein lipidation, and C-terminal protein amino acid modification. Each is linked with ALDH5A1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ALDH5A1-to-partner and partner-to-ALDH5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to triglyceride grouped by ALDH5A1-low versus ALDH5A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH5A1→partner) and Y-score (partner→ALDH5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to triglyceride →	-0.322	-2.323	<.001	<.001	3	15
LIVER	C-terminal protein lipidation →	-0.273	-2.073	<.001	<.001	3	14
LIVER	C-terminal protein amino acid modification →	-0.238	-1.932	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.073	+1.793	.003	<.001	3	12
LIVER	RNA stabilization →	+0.079	+2.162	<.001	<.001	3	12
OESOPHAGUS	Negative regulation of mRNA catabolic process →	+0.080	+1.716	.003	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,116 associations by consensus.

Response to triglyceride by ALDH5A1 expression — LIVER

Explore this box plot interactively →