ALDH3B2

Across TCGA pan-cancer cohorts, ALDH3B2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ALDH3B2 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ALDH3B2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ALDH3B2 expression acts as an unfavorable survival marker.

COAD, READ, and PRAD are the cancer types where ALDH3B2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.316	0.760	<.001	27	view →
READ	DFS	Median	II,III,IV	0.112	0.800	.002	6	view →
PRAD	DFS	Median	All	0.617	0.886	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ALDH3B2–COAD (DFS)

Open the COAD breakdown →