ALDH3B2

Across TCGA cell cohorts, ALDH3B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,418 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ALDH3B2-associated GO terms across cancer lineages are Foam cell differentiation, Phosphatidylinositol 3-kinase/protein kinase B signal transduction, and Positive regulation of excitatory synapse assembly. Each is linked with ALDH3B2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ALDH3B2-to-partner and partner-to-ALDH3B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Foam cell differentiation grouped by ALDH3B2-low versus ALDH3B2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3B2→partner) and Y-score (partner→ALDH3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Foam cell differentiation →	-0.249	-3.113	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol 3-kinase/protein kinase B signal transduction →	+0.044	+1.380	<.001	<.001	3	9
BREAST	Positive regulation of excitatory synapse assembly →	+1.034	+3.387	<.001	<.001	3	8
STOMACH	T cell mediated cytotoxicity →	+0.206	+1.164	<.001	.007	3	8
BLOOD_Leukemia	Regulation of inner ear receptor cell differentiation →	+1.028	+0.467	<.001	.007	3	8
BREAST	Pigment metabolic process involved in pigmentation →	-0.200	-2.999	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,418 associations by consensus.

Foam cell differentiation by ALDH3B2 expression — BREAST

Explore this box plot interactively →