ALDH3A1

Across TCGA patient cohorts, ALDH3A1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,852 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALDH3A1-associated genes across cancer lineages are AKR1C2, GPX2, and NQO1. Each is linked with ALDH3A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALDH3A1-to-partner and partner-to-ALDH3A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH3A1 versus AKR1C2 in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3A1→partner) and Y-score (partner→ALDH3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1C2 →	+3.502	+1.977	<.001	<.001	3	5
LSCC	GPX2 →	+3.031	+2.112	<.001	<.001	3	5
LSCC	NQO1 →	+2.521	+2.144	<.001	<.001	3	5
LSCC	AKR1C3 →	+3.167	+1.899	<.001	<.001	3	5
LSCC	AKR1B10 →	+4.388	+2.164	<.001	<.001	3	5
HNSC	LINC01269 →	+0.981	+1.038	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,852 associations by consensus.

ALDH3A1 vs AKR1C2 — LSCC

Explore this scatter interactively →