ALDH3A1

Across TCGA patient cohorts, ALDH3A1 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH3A1-associated genes across cancer lineages are Rab11, Cyclin-B1, and MYH11. Each is linked with ALDH3A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALDH3A1-to-partner and partner-to-ALDH3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab11 grouped by ALDH3A1-low versus ALDH3A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3A1→partner) and Y-score (partner→ALDH3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab11 →	-0.136	-1.980	.016	.030	3	3
UCEC	Cyclin-B1 →	+0.497	+3.169	.024	.018	3	2
SKCM	MYH11 →	-0.848	-3.169	.028	.017	3	1
SKCM	P-Cadherin →	+0.241	+3.000	.033	.035	3	1
SKCM	YAP_pS127 →	-0.319	-2.700	.047	.006	3	1
UCEC	JNK2 →	+0.226	+2.196	.003	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Rab11 by ALDH3A1 expression — UCEC

Explore this box plot interactively →