ALDH2

Across TCGA patient cohorts, ALDH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,991 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALDH2-associated proteins across cancer lineages are GPD1, JAK1, and PSMD2. Each is linked with ALDH2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ALDH2-to-partner and partner-to-ALDH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH2 versus GPD1 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH2→partner) and Y-score (partner→ALDH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPD1 →	+1.672	+1.017	<.001	<.001	3	7
GBM	JAK1 →	+0.366	+0.667	<.001	<.001	3	6
GBM	PSMD2 →	-0.180	-0.696	<.001	<.001	3	6
GBM	CRYL1 →	+0.663	+0.865	<.001	<.001	3	6
GBM	DDAH1 →	+0.626	+0.750	<.001	<.001	3	6
LUAD	TLR3 →	+0.505	+0.598	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,991 associations by consensus.

ALDH2 vs GPD1 — OV

Explore this scatter interactively →