ALDH2

Across TCGA patient cohorts, ALDH2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,851 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ALDH2-associated genes across cancer lineages are GPD1, ADH1B, and CDC20. Each is linked with ALDH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALDH2-to-partner and partner-to-ALDH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH2 versus GPD1 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH2→partner) and Y-score (partner→ALDH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPD1 →	+1.620	+0.656	<.001	.002	3	6
OV	ADH1B →	+2.411	+0.625	<.001	<.001	3	6
COAD	CDC20 →	-0.934	-0.664	<.001	<.001	3	5
GBM	DLGAP5 →	-1.125	-0.546	.001	.001	3	5
GBM	ALAD →	+0.528	+0.716	<.001	<.001	3	5
OV	JAM2 →	+0.688	+0.662	.005	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,851 associations by consensus.

ALDH2 vs GPD1 — OV

Explore this scatter interactively →