ALDH1L2

Across TCGA patient cohorts, ALDH1L2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,121 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALDH1L2-associated genes across cancer lineages are AMPD1, IGKV2-28, and LAX1. Each is linked with ALDH1L2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALDH1L2-to-partner and partner-to-ALDH1L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH1L2 versus AMPD1 in HNSC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1L2→partner) and Y-score (partner→ALDH1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AMPD1 →	+1.485	+0.560	<.001	<.001	3	8
OV	IGKV2-28 →	+1.851	+0.725	<.001	<.001	3	8
UCEC	LAX1 →	+1.294	+0.821	<.001	<.001	3	7
UCEC	IRF4 →	+1.549	+0.816	<.001	<.001	3	7
HNSC	FCRL5 →	+1.397	+0.603	<.001	<.001	3	7
OV	IGKC →	+2.787	+0.610	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,121 associations by consensus.

ALDH1L2 vs AMPD1 — HNSC

Explore this scatter interactively →