ALDH1L2

Across TCGA cell cohorts, ALDH1L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,744 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ALDH1L2-associated GO terms across cancer lineages are Pteridine-containing compound catabolic process, Folic acid-containing compound catabolic process, and 10-formyltetrahydrofolate catabolic process. Each is linked with ALDH1L2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ALDH1L2-to-partner and partner-to-ALDH1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pteridine-containing compound catabolic process grouped by ALDH1L2-low versus ALDH1L2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1L2→partner) and Y-score (partner→ALDH1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Pteridine-containing compound catabolic process →	-0.244	-1.918	<.001	<.001	3	11
URINARY_TRACT	Folic acid-containing compound catabolic process →	-0.244	-1.918	<.001	<.001	3	11
KIDNEY	10-formyltetrahydrofolate catabolic process →	-0.272	-1.592	<.001	.002	3	11
BONE	Liver development →	+0.075	+2.016	.003	.002	3	10
KIDNEY	Hepaticobiliary system development →	+0.096	+1.650	<.001	.006	3	9
BONE	Cotranslational protein targeting to membrane →	+0.131	+2.209	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,744 associations by consensus.

Pteridine-containing compound catabolic process by ALDH1L2 expression — URINARY_TRACT

Explore this box plot interactively →