ALDH1L1-AS1

Across TCGA pan-cancer cohorts, ALDH1L1-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ALDH1L1-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ALDH1L1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALDH1L1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

THCA, CHOL, and READ are the cancer types where ALDH1L1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.537	0.978	<.001	51	view →
CHOL	OS	Tertile	II,III,IV	0.216	0.703	.005	45	view →
READ	OS	Tertile	III,IV	0.253	0.857	<.001	45	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
ACC	DFS	Quartile	All	0.156	0.654	.009	24	view →
COAD	OS	Tertile	All	0.739	0.885	.012	18	view →
LGG	DFS	Quartile	All	0.747	0.854	.003	18	view →
LUAD	DFS	Tertile	IV	0.140	0.603	.021	18	view →
KIRC	OS	Median	All	0.905	0.854	.013	11	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	9	view →
PAAD	DFS	Quartile	All	0.564	0.320	.030	8	view →
BLCA	OS	Quartile	II,III,IV	0.792	0.674	.021	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ALDH1L1-AS1–THCA (OS)

Open the THCA breakdown →