Across TCGA patient cohorts, ALDH1A3 mutation is significantly associated with the RNA expression of many other genes, with 3,327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH1A3-associated genes across cancer lineages are GINS3, NOP10, and MCMBP. Each is linked with ALDH1A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH1A3-to-partner and partner-to-ALDH1A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1A3→partner) and Y-score (partner→ALDH1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS3 →	+0.647	+2.343	<.001	<.001	3	2
UCEC	NOP10 →	+0.495	+4.291	<.001	<.001	3	2
UCEC	MCMBP →	+0.410	+1.860	.001	<.001	3	2
UCEC	C4orf46 →	+0.533	+2.072	<.001	<.001	3	2
UCEC	IGHD5-5 →	+0.119	+3.978	<.001	.004	3	2
UCEC	SNORD90 →	+0.191	+1.670	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,327 associations by consensus.

Exploration

ALDH1A3 survival (RNA) · tumor vs normal (RNA) · all ALDH1A3 data types