Across TCGA patient cohorts, ALDH1A3 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH1A3-associated genes across cancer lineages are eIF4E, eIF4G, and FoxM1. Each is linked with ALDH1A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALDH1A3-to-partner and partner-to-ALDH1A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1A3→partner) and Y-score (partner→ALDH1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.198	+3.820	.005	<.001	3	3
UCEC	eIF4G →	+0.246	+2.321	.017	.033	3	2
UCEC	FoxM1 →	+0.228	+2.459	.008	.018	3	2
UCEC	PCNA →	+0.279	+4.169	<.001	<.001	3	2
UCEC	PDCD4 →	-0.396	-1.874	.012	.049	3	2
UCEC	Annexin-1 →	+0.560	+2.019	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ALDH1A3 survival (RNA) · tumor vs normal (RNA) · all ALDH1A3 data types