Across TCGA cell cohorts, ALDH1A3 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALDH1A3-associated genes across cancer lineages are SLC5A5, SDR9C7, and GPR27. Each is linked with ALDH1A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH1A3-to-partner and partner-to-ALDH1A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1A3→partner) and Y-score (partner→ALDH1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC5A5 →	+0.337	+2.716	<.001	.009	3	1
LARGE_INTESTINE	SDR9C7 →	+0.095	+3.555	.008	.003	3	1
LARGE_INTESTINE	GPR27 →	+1.017	+3.646	<.001	.002	3	1
LARGE_INTESTINE	TRHR →	+0.044	+3.169	<.001	.002	3	1
LARGE_INTESTINE	TFDP3 →	+0.024	+2.933	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.209	+2.688	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

ALDH1A3 survival (RNA) · tumor vs normal (RNA) · all ALDH1A3 data types