ALDH1A2

Across TCGA patient cohorts, ALDH1A2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,137 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ALDH1A2-associated genes across cancer lineages are FAT3, CHRDL1, and MEDAG. Each is linked with ALDH1A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALDH1A2-to-partner and partner-to-ALDH1A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDH1A2 versus FAT3 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1A2→partner) and Y-score (partner→ALDH1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAT3 →	+1.163	+0.432	<.001	<.001	3	6
BRCA	CHRDL1 →	+1.651	+0.934	<.001	<.001	3	5
OV	MEDAG →	+1.631	+0.698	<.001	<.001	3	5
UCEC	ASPA →	+0.603	+0.767	<.001	<.001	3	5
UCEC	C7 →	+1.887	+0.753	<.001	<.001	3	5
OV	PDE1A →	+0.874	+0.588	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,137 associations by consensus.

ALDH1A2 vs FAT3 — LSCC

Explore this scatter interactively →