ALDH1A2

Across TCGA cell cohorts, ALDH1A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,559 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALDH1A2-associated GO terms across cancer lineages are Regulation of response to endoplasmic reticulum stress, mRNA stabilization, and Vacuolar transport. Each is linked with ALDH1A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ALDH1A2-to-partner and partner-to-ALDH1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of response to endoplasmic reticulum stress grouped by ALDH1A2-low versus ALDH1A2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH1A2→partner) and Y-score (partner→ALDH1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of response to endoplasmic reticulum stress →	+0.070	+2.188	.004	.001	2	10
SOFT_TISSUE	mRNA stabilization →	+0.091	+1.475	<.001	.001	3	7
LIVER	Vacuolar transport →	+0.071	+3.445	<.001	<.001	3	7
LIVER	Lysosomal transport →	+0.075	+3.001	<.001	.008	3	7
OESOPHAGUS	Regulation of myoblast fusion →	+0.092	+0.993	.003	<.001	3	7
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.094	+0.882	.009	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,559 associations by consensus.

Regulation of response to endoplasmic reticulum stress by ALDH1A2 expression — LIVER

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