ALDH16A1

Across TCGA patient cohorts, ALDH16A1 mutation is significantly associated with the RNA expression of many other genes, with 894 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH16A1-associated genes across cancer lineages are MIR6070, CRYBB2P1, and OR8B6P. Each is linked with ALDH16A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALDH16A1-to-partner and partner-to-ALDH16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6070 grouped by ALDH16A1-low versus ALDH16A1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH16A1→partner) and Y-score (partner→ALDH16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR6070 →	+0.308	+4.878	<.001	.005	3	3
UCEC	CRYBB2P1 →	+0.450	+2.329	.003	.003	3	3
LUAD	OR8B6P →	+0.052	+4.315	<.001	.007	3	3
COAD	NCR1 →	+0.666	+3.223	<.001	.009	3	2
UCEC	TRAJ10 →	+0.691	+2.091	<.001	.001	3	2
COAD	CD24P1 →	+0.128	+3.135	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 894 associations by consensus.

MIR6070 by ALDH16A1 expression — LIHC

Explore this box plot interactively →