ALDH16A1

Across TCGA cell cohorts, ALDH16A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,766 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALDH16A1-associated GO terms across cancer lineages are DNA replication proofreading, Negative regulation of DNA-templated transcription, elongation, and Regulation of calcium ion export across plasma membrane. Each is linked with ALDH16A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ALDH16A1-to-partner and partner-to-ALDH16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by ALDH16A1-low versus ALDH16A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH16A1→partner) and Y-score (partner→ALDH16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication proofreading →	+0.170	+0.972	<.001	<.001	3	13
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.144	+1.367	<.001	<.001	3	13
BLOOD_Myeloma	Regulation of calcium ion export across plasma membrane →	+0.094	+0.805	<.001	.002	3	12
URINARY_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.069	+1.071	.001	.002	2	13
BONE	Regulation of glucose mediated signaling pathway →	+0.100	+1.019	<.001	<.001	3	11
BONE	Positive regulation of glucose mediated signaling pathway →	+0.100	+1.019	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,766 associations by consensus.

DNA replication proofreading by ALDH16A1 expression — BONE

Explore this box plot interactively →