ALB

Across TCGA patient cohorts, ALB mutation is significantly associated with the RNA expression of many other genes, with 3,538 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALB-associated genes across cancer lineages are DOC2B, OPRL1, and HHIPL1. Each is linked with ALB in more than 2 cancer types. Because this analysis shows association rather than direction, both ALB-to-partner and partner-to-ALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DOC2B grouped by ALB-low versus ALB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALB→partner) and Y-score (partner→ALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DOC2B →	-0.960	-2.226	<.001	.001	3	3
UCEC	OPRL1 →	-0.431	-2.071	.002	.005	3	3
LIHC	HHIPL1 →	-0.379	-3.079	.002	<.001	3	3
SKCM	ZNF423 →	-0.383	-1.302	.002	.005	3	3
SKCM	ATP1B2 →	-1.144	-1.488	.001	.001	3	3
UCEC	KLHL3 →	-0.452	-1.815	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,538 associations by consensus.

DOC2B by ALB expression — UCEC

Explore this box plot interactively →