ALB

Across TCGA patient cohorts, ALB mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALB-associated genes across cancer lineages are PDCD4, INPP4B, and p38-MAPK_pT180_Y182. Each is linked with ALB in more than 2 cancer types. Because this analysis shows association rather than direction, both ALB-to-partner and partner-to-ALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ALB-low versus ALB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALB→partner) and Y-score (partner→ALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.535	-1.652	<.001	.006	3	3
UCEC	INPP4B →	-0.313	-2.999	.003	<.001	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.365	-1.638	.013	.006	3	2
UCEC	ATM →	-0.435	-3.000	.003	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.484	+2.341	.013	.003	3	2
UCEC	4E-BP1 →	+0.210	+2.614	.018	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

PDCD4 by ALB expression — UCEC

Explore this box plot interactively →