ALB

Across TCGA cell cohorts, ALB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,789 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible ALB-associated GO terms across cancer lineages are Cellular response to calcium ion starvation, Negative regulation of cholesterol import, and Ventricular cardiac muscle cell action potential. Each is linked with ALB in more than 11 cancer types. Because this analysis shows association rather than direction, both ALB-to-partner and partner-to-ALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to calcium ion starvation grouped by ALB-low versus ALB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALB→partner) and Y-score (partner→ALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cellular response to calcium ion starvation →	-0.202	-0.633	.001	.004	2	12
LIVER	Negative regulation of cholesterol import →	+1.692	+7.564	<.001	<.001	3	7
OVARY	Ventricular cardiac muscle cell action potential →	-0.144	-0.412	.004	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Promoter clearance during DNA-templated transcription →	+0.108	+0.492	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	RNA polymerase II promoter clearance →	+0.108	+0.492	<.001	.001	3	5
OVARY	Aerobic electron transport chain →	+0.081	+0.438	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,789 associations by consensus.

Cellular response to calcium ion starvation by ALB expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →