ALB

Across TCGA cell cohorts, ALB mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALB-associated genes across cancer lineages are ADAM2, KRTAP19-3, and MSGN1. Each is linked with ALB in more than 1 cancer types. Because this analysis shows association rather than direction, both ALB-to-partner and partner-to-ALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM2 grouped by ALB-low versus ALB-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALB→partner) and Y-score (partner→ALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ADAM2 →	+0.046	+5.754	<.001	.002	3	1
CNS	KRTAP19-3 →	+0.116	+5.321	<.001	.005	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.061	+3.994	<.001	.002	3	1
LUNG_NSCLC_LUAD	GFRA4 →	+0.036	+5.662	<.001	.002	3	1
LUNG_SCLC	OR5H2 →	+0.050	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ADAM2 by ALB expression — CNS

Explore this box plot interactively →