ALAS2

Across TCGA cell cohorts, ALAS2 RNA expression is significantly associated with the RNA expression of many other genes, with 4,079 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALAS2-associated genes across cancer lineages are MORC3, CMTM5, and EPB42. Each is linked with ALAS2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALAS2-to-partner and partner-to-ALAS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALAS2 versus MORC3 in BLOOD_Leukemia, with a Pearson correlation of 0.55.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALAS2→partner) and Y-score (partner→ALAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MORC3 →	+0.712	+1.846	<.001	<.001	3	3
BLOOD_Leukemia	CMTM5 →	+1.329	+2.210	<.001	<.001	3	3
BLOOD_Leukemia	EPB42 →	+1.370	+2.267	<.001	<.001	3	3
BLOOD_Leukemia	HBA2 →	+2.866	+2.115	<.001	<.001	3	3
BLOOD_Leukemia	HBG2 →	+4.349	+2.054	<.001	<.001	3	3
BLOOD_Leukemia	HBA1 →	+3.482	+2.148	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,079 associations by consensus.

ALAS2 vs MORC3 — BLOOD_Leukemia

Explore this scatter interactively →