ALAD

Across TCGA patient cohorts, ALAD RNA expression is significantly associated with the protein abundance of many other proteins, with 18,931 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALAD-associated proteins across cancer lineages are PTPA, RAB14, and ALAD_S215. Each is linked with ALAD in more than 6 cancer types. Because this analysis shows association rather than direction, both ALAD-to-partner and partner-to-ALAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALAD versus PTPA in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALAD→partner) and Y-score (partner→ALAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPA →	+0.330	+0.737	<.001	<.001	3	7
LUAD	RAB14 →	+0.298	+0.657	<.001	<.001	3	7
BRCA	ALAD_S215 →	+0.744	+0.621	<.001	<.001	3	7
OV	BSPRY →	+0.837	+0.497	<.001	.008	3	7
BRCA	HSDL2 →	+0.461	+0.615	<.001	<.001	3	7
GBM	ZER1 →	+0.279	+0.338	.006	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,931 associations by consensus.

ALAD vs PTPA — BRCA

Explore this scatter interactively →