Across TCGA patient cohorts, AKT1S1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,507 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AKT1S1-associated proteins across cancer lineages are PRMT1, TRIM28, and PPP5C. Each is linked with AKT1S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKT1S1-to-partner and partner-to-AKT1S1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT1S1→partner) and Y-score (partner→AKT1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRMT1 →	+0.295	+0.267	.001	.007	3	6
GBM	TRIM28 →	+0.307	+0.274	<.001	<.001	3	5
OV	PPP5C →	+0.331	+0.671	.002	<.001	3	4
UCEC	SMC2 →	+0.569	+0.409	<.001	.001	3	4
OV	PNKP →	+0.281	+0.495	<.001	<.001	3	4
GBM	MEPCE →	+0.207	+0.203	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,507 associations by consensus.

Exploration

AKT1S1 survival (RNA) · tumor vs normal (RNA) · all AKT1S1 data types