Across TCGA patient cohorts, AKT1S1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,094 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKT1S1-associated genes across cancer lineages are MYH13, CCDC80, and GXYLT2. Each is linked with AKT1S1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AKT1S1-to-partner and partner-to-AKT1S1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT1S1→partner) and Y-score (partner→AKT1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYH13 →	+0.347	+0.268	.007	<.001	3	4
BRCA	CCDC80 →	+0.961	+0.253	.001	.004	3	4
CCRCC	GXYLT2 →	+1.032	+0.113	<.001	.005	3	4
LSCC	LGALS1 →	+0.496	+0.143	.003	.003	3	3
BRCA	MXRA5 →	+1.094	+0.263	.001	.007	2	4
CCRCC	IGDCC4 →	+0.660	+0.144	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,094 associations by consensus.

Exploration

AKT1S1 survival (RNA) · tumor vs normal (RNA) · all AKT1S1 data types