Across TCGA cell cohorts, AKT1S1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,253 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKT1S1-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Negative regulation of calcium ion export across plasma membrane, and Negative regulation of hyaluronan biosynthetic process. Each is linked with AKT1S1 in more than 11 cancer types. Because this analysis shows association rather than direction, both AKT1S1-to-partner and partner-to-AKT1S1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT1S1→partner) and Y-score (partner→AKT1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Calcium-independent cell-matrix adhesion →	+0.179	+0.943	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.054	+0.603	.001	.004	3	12
SOFT_TISSUE	Negative regulation of hyaluronan biosynthetic process →	+0.154	+0.779	<.001	<.001	3	11
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.144	+0.769	<.001	<.001	3	11
SOFT_TISSUE	Peptidyl-methionine modification →	+0.179	+0.826	<.001	<.001	3	11
SOFT_TISSUE	Negative regulation of NLRP3 inflammasome complex assembly →	+0.143	+0.932	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,253 associations by consensus.

Exploration

AKT1S1 survival (RNA) · tumor vs normal (RNA) · all AKT1S1 data types