Across TCGA cell cohorts, AKT1S1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,753 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible AKT1S1-associated genes across cancer lineages are UBN2, IVNS1ABP, and SEPTIN5. Each is linked with AKT1S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKT1S1-to-partner and partner-to-AKT1S1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKT1S1→partner) and Y-score (partner→AKT1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	UBN2 →	+0.898	+0.771	<.001	<.001	3	6
URINARY_TRACT	IVNS1ABP →	+0.936	+0.884	.005	<.001	3	6
BLOOD_Lymphoma	SEPTIN5 →	+1.544	+0.747	<.001	<.001	3	6
BLOOD_Lymphoma	ZNF74 →	+1.533	+0.524	<.001	.002	3	6
LUNG_SCLC	RBMX →	+0.539	+0.732	<.001	.002	3	6
URINARY_TRACT	KIF27 →	+0.683	+0.626	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Exploration

AKT1S1 survival (RNA) · tumor vs normal (RNA) · all AKT1S1 data types