AKR7A3

Across TCGA patient cohorts, AKR7A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,492 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AKR7A3-associated proteins across cancer lineages are TLR2, PARVG, and PLEK. Each is linked with AKR7A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both AKR7A3-to-partner and partner-to-AKR7A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKR7A3 versus TLR2 in CCRCC, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR7A3→partner) and Y-score (partner→AKR7A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TLR2 →	-0.470	-1.681	<.001	<.001	3	7
GBM	PARVG →	-0.635	-0.594	<.001	<.001	3	6
CCRCC	PLEK →	-0.511	-1.483	<.001	<.001	3	6
COAD	TCEA3 →	+0.758	+1.084	<.001	<.001	3	6
GBM	TNFAIP8 →	-0.489	-0.363	.005	.006	3	6
HNSC	CASP1 →	-0.469	-0.683	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,492 associations by consensus.

AKR7A3 vs TLR2 — CCRCC

Explore this scatter interactively →