AKR7A3

Across TCGA cell cohorts, AKR7A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,387 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AKR7A3-associated GO terms across cancer lineages are Aflatoxin catabolic process, Mycotoxin catabolic process, and Fatty acid beta-oxidation. Each is linked with AKR7A3 in more than 16 cancer types. Because this analysis shows association rather than direction, both AKR7A3-to-partner and partner-to-AKR7A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aflatoxin catabolic process grouped by AKR7A3-low versus AKR7A3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR7A3→partner) and Y-score (partner→AKR7A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Aflatoxin catabolic process →	-0.274	-1.773	<.001	.001	3	17
OESOPHAGUS	Mycotoxin catabolic process →	-0.274	-1.773	<.001	.001	3	17
STOMACH	Fatty acid beta-oxidation →	+0.102	+2.529	.003	.001	3	10
OESOPHAGUS	Toxin catabolic process →	-0.226	-1.582	<.001	.004	2	11
OESOPHAGUS	Mycotoxin metabolic process →	-0.208	-1.303	.003	.003	3	10
OESOPHAGUS	Aflatoxin metabolic process →	-0.208	-1.303	.003	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,387 associations by consensus.

Aflatoxin catabolic process by AKR7A3 expression — OESOPHAGUS

Explore this box plot interactively →