AKR1E2

Across TCGA patient cohorts, AKR1E2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,675 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKR1E2-associated proteins across cancer lineages are TSPYL5, UCHL1, and ZZEF1. Each is linked with AKR1E2 in more than 3 cancer types. Because this analysis shows association rather than direction, both AKR1E2-to-partner and partner-to-AKR1E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKR1E2 versus TSPYL5 in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1E2→partner) and Y-score (partner→AKR1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPYL5 →	+0.775	+0.907	<.001	.001	3	4
OV	UCHL1 →	+1.219	+1.075	<.001	<.001	3	4
BRCA	ZZEF1 →	-0.244	-0.902	<.001	.002	3	3
GBM	TRIM3 →	+0.262	+0.410	<.001	.001	3	3
BRCA	NRBF2 →	+0.267	+0.889	<.001	<.001	3	3
BRCA	PFKP →	+0.648	+1.070	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,675 associations by consensus.

AKR1E2 vs TSPYL5 — BRCA

Explore this scatter interactively →