AKR1D1

Across TCGA cell cohorts, AKR1D1 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,011 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible AKR1D1-associated GO terms across cancer lineages are Terpenoid catabolic process, Progesterone metabolic process, and Cellular response to jasmonic acid stimulus. Each is linked with AKR1D1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AKR1D1-to-partner and partner-to-AKR1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Terpenoid catabolic process grouped by AKR1D1-low versus AKR1D1-high in LUNG_NSCLC_LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1D1→partner) and Y-score (partner→AKR1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Terpenoid catabolic process →	+0.397	+3.126	<.001	.001	3	7
OVARY	Progesterone metabolic process →	+0.506	+2.140	.006	.004	2	8
OVARY	Cellular response to jasmonic acid stimulus →	+0.700	+2.140	<.001	.004	2	7
LUNG_NSCLC_LUAD	Isoprenoid catabolic process →	+0.380	+2.635	<.001	.002	3	6
OVARY	Response to jasmonic acid →	+0.700	+2.140	<.001	.004	2	7
LUNG_NSCLC_LUAD	Sesquiterpenoid metabolic process →	+0.324	+3.590	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,011 associations by consensus.

Terpenoid catabolic process by AKR1D1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →