Across TCGA cell cohorts, AKR1C4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKR1C4-associated GO terms across cancer lineages are Cellular response to jasmonic acid stimulus, Response to jasmonic acid, and Isoprenoid catabolic process. Each is linked with AKR1C4 in more than 8 cancer types. Because this analysis shows association rather than direction, both AKR1C4-to-partner and partner-to-AKR1C4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1C4→partner) and Y-score (partner→AKR1C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cellular response to jasmonic acid stimulus →	+1.732	+0.448	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Response to jasmonic acid →	+1.732	+0.448	<.001	<.001	3	9
LARGE_INTESTINE	Isoprenoid catabolic process →	+1.186	+1.195	<.001	.001	3	9
LUNG_NSCLC_LUAD	Response to prostaglandin D →	+0.857	+0.473	<.001	.003	3	8
LUNG_NSCLC_LUAD	Cellular response to prostaglandin D stimulus →	+0.857	+0.473	<.001	.003	3	8
LARGE_INTESTINE	Regulation of retinoic acid biosynthetic process →	+0.197	+0.887	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,257 associations by consensus.

Exploration

AKR1C4 survival (RNA) · tumor vs normal (RNA) · all AKR1C4 data types