Across TCGA cell cohorts, AKR1C3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,909 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible AKR1C3-associated GO terms across cancer lineages are Response to jasmonic acid, Cellular response to jasmonic acid stimulus, and Isoprenoid catabolic process. Each is linked with AKR1C3 in more than 19 cancer types. Because this analysis shows association rather than direction, both AKR1C3-to-partner and partner-to-AKR1C3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1C3→partner) and Y-score (partner→AKR1C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Response to jasmonic acid →	+1.923	+5.705	<.001	<.001	3	20
LUNG_NSCLC_LUAD	Cellular response to jasmonic acid stimulus →	+1.923	+5.705	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Isoprenoid catabolic process →	+1.590	+6.756	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Terpenoid catabolic process →	+1.569	+6.756	<.001	<.001	3	19
LUNG_NSCLC_LUAD	Testosterone biosynthetic process →	+1.840	+5.823	<.001	<.001	3	19
BREAST	Response to prostaglandin D →	+1.329	+3.379	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,909 associations by consensus.

Exploration

AKR1C3 survival (RNA) · tumor vs normal (RNA) · all AKR1C3 data types