AKR1C1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AKR1C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,976 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible AKR1C1-associated GO terms across cancer lineages are Cellular response to jasmonic acid stimulus, Response to jasmonic acid, and Terpenoid catabolic process. Each is linked with AKR1C1 in more than 18 cancer types. Because this analysis shows association rather than direction, both AKR1C1-to-partner and partner-to-AKR1C1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1C1→partner) and Y-score (partner→AKR1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADCellular response to jasmonic acid stimulus →+1.822+5.634<.001<.001319
LUNG_NSCLC_LUADResponse to jasmonic acid →+1.822+5.634<.001<.001319
LUNG_NSCLC_LUSCTerpenoid catabolic process →+1.525+6.781<.001<.001318
BONETestosterone biosynthetic process →+1.884+3.210<.001<.001318
BREASTResponse to prostaglandin D →+1.191+2.313<.001<.001318
BREASTCellular response to prostaglandin D stimulus →+1.191+2.313<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,976 associations by consensus.

Exploration