AKR1B1P6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AKR1B1P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,571 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AKR1B1P6-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Electron transport chain, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with AKR1B1P6 in more than 13 cancer types. Because this analysis shows association rather than direction, both AKR1B1P6-to-partner and partner-to-AKR1B1P6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P6→partner) and Y-score (partner→AKR1B1P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRibose phosphate biosynthetic process →+0.069+0.207<.001<.001314
STADElectron transport chain →+0.071+0.229<.001<.001314
STADPositive regulation of canonical NF-kappaB signal transduction →+0.064+0.181<.001<.001314
STADRegulation of protein serine/threonine kinase activity →+0.058+0.203<.001<.001313
STADNucleoside phosphate biosynthetic process →+0.064+0.206<.001<.001312
STADAlpha-amino acid metabolic process →+0.039+0.238<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,571 associations by consensus.

Exploration