AKR1B1P5

Across TCGA patient cohorts, AKR1B1P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,499 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AKR1B1P5-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, DNA damage response, signal transduction by p53 class mediator, and Positive regulation of protein polymerization. Each is linked with AKR1B1P5 in more than 10 cancer types. Because this analysis shows association rather than direction, both AKR1B1P5-to-partner and partner-to-AKR1B1P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by AKR1B1P5-low versus AKR1B1P5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P5→partner) and Y-score (partner→AKR1B1P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside triphosphate metabolic process →	+0.071	+0.164	<.001	<.001	3	11
STAD	DNA damage response, signal transduction by p53 class mediator →	+0.069	+0.150	<.001	<.001	3	11
STAD	Positive regulation of protein polymerization →	+0.068	+0.161	<.001	<.001	3	11
STAD	Signal transduction in response to DNA damage →	+0.072	+0.153	<.001	<.001	3	11
STAD	Receptor-mediated endocytosis →	+0.055	+0.154	<.001	<.001	3	11
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.069	+0.173	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,499 associations by consensus.

Nucleoside triphosphate metabolic process by AKR1B1P5 expression — STAD

Explore this box plot interactively →