AKR1B1P4

Across TCGA patient cohorts, AKR1B1P4 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,623 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKR1B1P4-associated proteins across cancer lineages are ANXA3_S19, MTRES1_S116, and PARN_S628. Each is linked with AKR1B1P4 in more than 2 cancer types. Because this analysis shows association rather than direction, both AKR1B1P4-to-partner and partner-to-AKR1B1P4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKR1B1P4 versus ANXA3_S19 in LSCC, with a Pearson correlation of -0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P4→partner) and Y-score (partner→AKR1B1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANXA3_S19 →	-0.999	-0.276	.002	.007	3	2
HNSC	MTRES1_S116 →	+0.773	+0.425	<.001	.006	3	2
LUAD	PARN_S628 →	+0.473	+0.224	.001	.003	3	2
GBM	ZHX3 →	-0.273	-0.052	<.001	.001	3	2
PDAC	RPA1_S384 →	+0.594	+0.266	<.001	.002	3	2
PDAC	RPRD1B_S166 →	+0.598	+0.161	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,623 associations by consensus.

AKR1B1P4 vs ANXA3_S19 — LSCC

Explore this scatter interactively →