AKR1B1P4

Across TCGA patient cohorts, AKR1B1P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,927 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AKR1B1P4-associated GO terms across cancer lineages are Macromolecule methylation, tRNA processing, and tRNA metabolic process. Each is linked with AKR1B1P4 in more than 13 cancer types. Because this analysis shows association rather than direction, both AKR1B1P4-to-partner and partner-to-AKR1B1P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by AKR1B1P4-low versus AKR1B1P4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P4→partner) and Y-score (partner→AKR1B1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Macromolecule methylation →	+0.059	+0.089	<.001	<.001	3	14
STAD	tRNA processing →	+0.061	+0.086	<.001	<.001	3	14
STAD	tRNA metabolic process →	+0.063	+0.086	<.001	<.001	3	13
STAD	Mitochondrial gene expression →	+0.070	+0.084	<.001	<.001	3	12
STAD	tRNA modification →	+0.058	+0.088	<.001	<.001	3	12
STAD	Amino acid activation →	+0.057	+0.074	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,927 associations by consensus.

Macromolecule methylation by AKR1B1P4 expression — STAD

Explore this box plot interactively →