Across TCGA patient cohorts, AKR1B1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,517 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AKR1B1P2-associated GO terms across cancer lineages are Oxidative phosphorylation, Iron-sulfur cluster assembly, and Electron transport chain. Each is linked with AKR1B1P2 in more than 13 cancer types. Because this analysis shows association rather than direction, both AKR1B1P2-to-partner and partner-to-AKR1B1P2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P2→partner) and Y-score (partner→AKR1B1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.060	+0.119	<.001	<.001	3	14
ESCA	Iron-sulfur cluster assembly →	+0.046	+0.193	.001	<.001	3	12
STAD	Electron transport chain →	+0.054	+0.124	<.001	<.001	3	12
STAD	Mitochondrial translation →	+0.056	+0.125	<.001	<.001	3	12
STAD	Aerobic respiration →	+0.058	+0.131	<.001	<.001	3	12
ESCA	Protein maturation by iron-sulfur cluster transfer →	+0.073	+0.202	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,517 associations by consensus.

Exploration

AKR1B1P2 survival (RNA) · tumor vs normal (RNA) · all AKR1B1P2 data types