Across TCGA patient cohorts, AKR1B15 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,927 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKR1B15-associated proteins across cancer lineages are AKR1B10, DSC2, and G6PD. Each is linked with AKR1B15 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKR1B15-to-partner and partner-to-AKR1B15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B15→partner) and Y-score (partner→AKR1B15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1B10 →	+2.249	+1.643	<.001	<.001	3	6
HNSC	DSC2 →	+0.822	+1.256	<.001	<.001	3	5
LSCC	G6PD →	+0.824	+1.330	<.001	<.001	3	5
LSCC	JUP →	+0.756	+1.604	<.001	<.001	3	4
LSCC	HTATIP2 →	+0.527	+1.534	<.001	<.001	3	4
LSCC	KRT16 →	+1.478	+1.423	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,927 associations by consensus.

Exploration

AKR1B15 survival (RNA) · tumor vs normal (RNA) · all AKR1B15 data types