AKIRIN1P1

Across TCGA pan-cancer cohorts, AKIRIN1P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of AKIRIN1P1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where AKIRIN1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types AKIRIN1P1 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, LUAD, and KIRC are the cancer types where AKIRIN1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AKIRIN1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.047	<.001	5	view →
LUAD	Female	II,III,IV	−0.133	.015	3	view →
KIRC	Male	All	−0.011	.025	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

AKIRIN1P1–THCA

Open the THCA breakdown →