AKIP1

Across TCGA patient cohorts, AKIP1 RNA expression is significantly associated with the mutation status of many other genes, with 12,665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKIP1-associated genes across cancer lineages are RNF213, TP53, and AHNAK. Each is linked with AKIP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AKIP1-to-partner and partner-to-AKIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF213 grouped by AKIP1-low versus AKIP1-high in STAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIP1→partner) and Y-score (partner→AKIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNF213 →	+2.049	+0.248	.004	.003	3	5
PRAD	TP53 →	+1.996	+0.209	.002	.001	3	4
HNSC	AHNAK →	+2.680	+0.360	<.001	<.001	3	4
UCEC	EP300 →	+1.144	+0.259	.002	.002	3	4
UCEC	NCOA3 →	+1.722	+0.458	<.001	<.001	3	4
UCEC	DNAH10 →	+1.449	+0.408	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,665 associations by consensus.

RNF213 by AKIP1 expression — STAD

Explore this box plot interactively →