AKIP1

Across TCGA patient cohorts, AKIP1 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible AKIP1-associated genes across cancer lineages are H4C7, MIR8076, and RN7SL100P. Each is linked with AKIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKIP1-to-partner and partner-to-AKIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H4C7 grouped by AKIP1-low versus AKIP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIP1→partner) and Y-score (partner→AKIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	H4C7 →	+0.141	+5.970	<.001	.002	3	1
SKCM	MIR8076 →	+0.442	+5.436	<.001	.005	3	1
SKCM	RN7SL100P →	+0.140	+5.362	<.001	.005	3	1
SKCM	RPS15AP34 →	+0.106	+5.159	<.001	.007	3	1
SKCM	NKAIN1P1 →	+0.367	+5.867	<.001	.003	3	1
UCEC	RNA5SP536 →	+0.249	+4.137	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

H4C7 by AKIP1 expression — SKCM

Explore this box plot interactively →