AKIP1

Across TCGA cell cohorts, AKIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,131 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AKIP1-associated GO terms across cancer lineages are Telomere localization, Telomere tethering at nuclear periphery, and Protein depolymerization. Each is linked with AKIP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both AKIP1-to-partner and partner-to-AKIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere localization grouped by AKIP1-low versus AKIP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIP1→partner) and Y-score (partner→AKIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Telomere localization →	+0.145	+0.863	<.001	.003	3	11
URINARY_TRACT	Telomere tethering at nuclear periphery →	+0.127	+0.627	<.001	.003	3	11
CNS	Protein depolymerization →	+0.102	+0.751	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Establishment or maintenance of cell polarity regulating cell shape →	+0.186	+1.133	.001	.001	3	9
BONE	Actin filament depolymerization →	+0.206	+0.877	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.205	+1.337	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,131 associations by consensus.

Telomere localization by AKIP1 expression — URINARY_TRACT

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